First of all, this story arc has the First Appearance of Gwen Stacy.
But it’s also got the first appearance of Harry Osborn, Aunt May dying because of Peter Parker (he gave her a blood transfusion that makes her sick), and Doc Ock being as villainous as ever…And it’s got one of the most famous sequences in history. Pages of Spider-Man struggling under the weight of a collapse, digging deep, and then….
If there’s one comic that shows the brilliance of Steve Ditko, it’s this one.
On a side note, Amazing Spider-Man #31 had the first appearance of The Jackal, so it’s indirectly responsible for the Clone Saga.
Take what you want from that.