For the giant-sized 100th issue of Marvel Team Up, Chris Claremont and Frank Miller teamed up to create … Karma.
The duo had already sent Wolverine to Japan, so introducing (the first?) a Vietnamese character into the Marvel Universe made a little sense–Miller has always been a bit of an Asianphile. The character has the ability to possess the bodies of others, so we get to see Spidey fight the Fantastic Four. Hero versus hero is always cool.
It ends on a family note. Karma would go on to be a founding member of Claremont’s New Mutants, and one of the first lesbians in comic book history.